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Which of the following are possible causes of histotoxic hypoxia?

1. Alcohol
2. Acceleration
3. Nausea
4. Heart attack
5. Self-medication
6. Low humidity
7. High humidity
8. COPD
9. Cyanide poisoning
10. Toxic liquids
11. Altitude
12. Arousal

  • A

    1, 5, 9 and 10.

  • B
    1, 6, 11 and 12.
  • C
    2, 3, 7 and 11.
  • D
    2, 4, 8 and 9.

Histotoxic hypoxia, also known as cytotoxic hypoxia - happens at the cell level. This means that the cell expecting and needing the oxygen is impaired and cannot use the oxygen to support metabolism.

This may occur in the case of poisoning by toxic fumes or liquids during an accident. However, it is more commonly observed in aviation with passengers due to excessive intake of alcohol or drugs and self-medication.

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